The INDUSEM Position Paper on the Emerging Electronic Waste Management Emergency

Electronic waste or e-waste is a severe and regarding challenge globally. Exponential improve in the manufacturing of those instrument have created a man-made downside of e-waste; United Nations has known as it as “tsunami of e-waste.” Informal administration and unsafe disposals have compounded the downside additional.

The hazardous chemical compounds, metals, and natural pollution launched from e-waste can result in severe well being penalties corresponding to organ injury, genetic defects, neuropsychiatric sickness, and most cancers. Problem of e-waste is colossal and must be seen as main public well being emergency. In India, use of digital instrument has elevated significantly with much less focus on formal waste administration and secure disposal.

This has created a serious well being hazard. International well being companies, Indian Council of MedicalResearch, e-waste regulating our bodies, educational institutes, and numerous authorities and non-government organizations ought to be a part of palms collectively to successfully handle the issues of e-waste. Swacch Bharat Abhiyan began by the honorable Prime Minster ought to think about e-waste as the prime most precedence by way of its secure administration and disposal.

2',3',5'-triacetyl-5-Azacytidine
B2822-5
EUR 153

2',3',5'-triacetyl-5-Azacytidine
C4119-5 5 mg
EUR 118
Description: 2',3',5'-triacetyl-5-Azacytidine (TAC) is the lead prodrug form of 5-azacytidine which may be rapidly absorbed after oral administration [1]. 5-Azacytidine is an inhibitor of DNA methyltransferase [2].

Aftin-5
2575-5
EUR 457

CHD-5
2693-5
EUR 153

Necrostatin-5
1865-5
EUR 126

GNF-5
B1329-5
EUR 142

Histatin 5
5-01307 4 x 1mg Ask for price

5-Iodotubercidin
A3125-5 5 mg
EUR 168
Description: 5-Iodotubercidin (Itu) is a purine derivative and hence an inhibitor of adenosine kinase with an IC50 value of 26 nM [1]. Adenosine kinase is important in regulating the intracellular and extracellular concentrations of adenosine and hence diverse physiological actions of adenosine [2].

5-ROX
B8212-5 5 mg
EUR 195

Thrombin Receptor Activator for Peptide 5 (TRAP-5)
A1036-5 5 mg
EUR 102
Description: Thrombin Receptor Activator for Peptide 5 (TRAP-5),(C30H50N8O7), a peptide with the sequence NH2-Ser-Phe-Leu-Leu-Arg-COOH, MW= 634.76. coagulation factor II (thrombin) receptor is a G protein-coupled receptor involved in the regulation of thrombotic response.

2',5'-Dideoxyadenosine
2770-5
EUR 240

[Cit5]-TRAP-5
5-00062 4 x 5mg Ask for price

A-VI-5
5-00524 4 x 5mg Ask for price

ACTH(5-10)
5-00605 4 x 5mg Ask for price

Angiotensin (1-5)
5-00676 4 x 5mg Ask for price

Bradykinin (1-5)
5-00852 4 x 5mg Ask for price

TRAP-5 amide
5-02019 4 x 5mg Ask for price

Teicoplanin A2-5
C4938-5 5 mg
EUR 1157
Description: Teicoplanin A2-5, derived from Actinoplanes teichomyceticus, is a glycopeptide antibiotic which produces a broad spectrum of antibiotic activity against gram-positive bacteria.

5'-deoxy Thymidine
C4692-5 5 mg
EUR 180
Description: 5'-Deoxy Thymidine has been used as a research tool for antiviral and anticancer studies. 5'-Deoxy Thymidine can be used to study the entry mechanism into human erythrocytes in comparison with other deoxythymidines.

5-fluoro 203
C4114-5 5 mg
EUR 154
Description: 5-fluoro 203 (5F-203) is an antitumor agent and cytotoxic compound that acts as a potent AhR agonist [1][2][3]. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in regulating xenobiotic-metabolizing enzymes such as cytochrome P450.

W-5 hydrochloride
B6277-5 5 mg
EUR 116

5-Nonyloxytryptamine oxalate
B6496-5 5 mg
EUR 154

5-Formylcytosine (5-fC) ELISA Kit
MET-5102-5 5 x 96 assays
EUR 2283

5-Carboxylcytosine (5-caC) ELISA Kit
MET-5103-5 5 x 96 assays
EUR 2283

AICA riboside, 5'-phosphate
9416-5
EUR 153

Individual Reaction Mix 5
G065-5 200 reactions
EUR 167

Necrosis Inhibitor, Necrox-5
2229-5
EUR 615

5-Nitroso-8-quinolinol
B2825-5
EUR 109

Dok- 5 (263 - 275)
5-01048 4 x 5mg Ask for price

Secretin (5 - 27), porcine
5-01917 4 x 1mg Ask for price

SH2 Domain Ligand (5)
5-01929 4 x 5mg Ask for price

Boc-5-Ava-OH
5-04607 25g Ask for price

Boc-5-Ava-OH
5-04608 100g Ask for price

Fmoc-5-Ava-OH
5-04609 5g Ask for price

Fmoc-5-Ava-OH
5-04610 25g Ask for price

FAM azide, 5- isomer
A8117-5 5 mg
EUR 166
Description: FAM azide for Click chemistry labeling. FAM remains one of the most popular fluorescent lablels for various application. Most instruments capable of fluorescence detection, ranging from plate readers to fluorescence microscopes, are able to work in FAM channel.

ROX azide, 5- isomer
A8126-5 5 mg
EUR 583
Description: ROX (rhodamine-X) azide, solid material, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. ROX is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield.Pure 5-isomer.

TAMRA azide, 5- isomer
A8129-5 5 mg
EUR 583
Description: TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. Pure 5-isomer.TAMRA is often used as FRET acceptor for FAM fluorophore.

5'-(N-Cyclopropyl)carboxamidoadenosine
C4645-5 5 mg
EUR 128

5-trans U-46619
C4261-5 5 mg
EUR 538
Description: 5-trans U-46619 is a minor impurity (2-5%) which variably exists in most commercial preparations of U-46619 [1]. U-46619 is a selective thromboxane A2 agonist involved in inducing platelet aggregation and vascular smooth muscle contraction [2].

2',5'-dideoxy Adenosine
C3993-5 5 mg
EUR 189
Description: 2',5'-dideoxy Adenosine, a nucleoside analog, is one of the first identified cell-permeable, P-site inhibitors of adenylate cyclase [1]. Adenylyl cyclase is an enzyme with key regulatory roles in almost all cells.

2-Methyl-5-hydroxytryptamine hydrochloride
2768-5
EUR 185

3,3',5'-Triiodo-L-thyronine
B2017-5
EUR 229

pLenti-CLDN1 shRNA-5 Plasmid
PVTBAV04867-5 2 ug
EUR 356

[Pyr5]-Substance P (5-11)
5-00288 4 x 5mg Ask for price

[Trp3, Arg5]-Ghrelin (1-5)
5-00313 4 x 5mg Ask for price

beta-Casomorphin (1-5) (bovine)
5-00475 4 x 5mg Ask for price

Angiotensin I/II (5-8)
5-00684 4 x 5mg Ask for price

Cholecystokinin Octapeptide (1-5) (desulfated)
5-00970 4 x 5mg Ask for price

HIV-gp41-Antigenic Peptide 5
5-01331 4 x 1mg Ask for price

Fmoc-Trp(5-OH)-OH
5-06939 5g Ask for price

Fmoc-Trp(5-OH)-OH
5-06940 25g Ask for price

Magnetic Beads (DNA) 5 mL
P920-5 - Ask for price

Angiotensin 1/2 (1-5)
A1047-5 5 mg
EUR 119
Description: Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.Angiotensin I is formed by the action ofreninonangiotensinogen, an ?-2-globulin with 12 amino acids.

Angiotensin 1/2 (5-7)
A1049-5 5 mg
EUR 119
Description: Angiotensin 1/2 (5-7), (C17H27N5O4), a peptide with the sequence H2N-Ile-His-Pro-OH, MW=365.43. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure.

3,3',5'-Triiodo-L-thyronine
C5014-5 5 mg
EUR 134
Description: 3,3',5'-triiodo-L-thyronine (reverse T3 or rT3) and 3,5,3'-triiodo-L-thyronine (T3) are the metabolism of thyroxine (T4) [1]. 3,3',5'-Triiodo-L-thyronine is thyroid hormone receptors TR? and TR? antagonist [1].

2'-O-Methylpseudouridine-5'-Triphosphate
B7993-.5 5x100 µl (100 mM)
EUR 14023

2'-Fluoro-thymidine-5'-Triphosphate
B8035-.5 5x100 µl (100 mM)
EUR 2059

Helioxanthin derivative 5-4-2
B4700-5 5 mg
EUR 683
Description: Helioxanthin derivative 5-4-2, an analogue of helioxanthin (ACH126447), is a small-molecule inhibitor of HBV, HSV-1and HSV-2 virus with EC50 values of 0.08 ?M, 0.29 ?M and 0.16 ?M, respectively [1].

5?-dihydro-11-keto Testosterone
C4317-5 5 mg
EUR 586
Description: 5?-dihydro-11-keto Testosterone (11KDHT) is a full androgen receptor agonist comparable to dihydrotestosterone (DHT) [1][2][3].

Nickel NTA Magnetic Agarose Bead (5%)
MagNTANi5-5 5ml suspension
EUR 174

beta-Casomorphin (1-5) amide (bovine)
5-00476 4 x 5mg Ask for price

cAMP Dependent PK Inhibitor (5-24)
5-00922 4 x 1mg Ask for price

Kinase Domain of Insulin Receptor (5)
5-01429 4 x 1mg Ask for price

Fmoc-D-Trp(5-Br)-OH
5-04217 1g Ask for price

Fmoc-D-Trp(5-Br)-OH
5-04218 5g Ask for price

Fmoc-D-Trp(5-Cl)-OH
5-04223 1g Ask for price

Fmoc-D-Trp(5-Cl)-OH
5-04224 5g Ask for price

Fmoc-D-Trp(5-F)-OH
5-04227 1g Ask for price

Fmoc-D-Trp(5-F)-OH
5-04228 5g Ask for price

Ac-DL-Trp(5-Br)-OH·DCHA
5-04229 1g Ask for price

Ac-DL-Trp(5-Br)-OH·DCHA
5-04230 5g Ask for price

Ac-DL-Trp(5-Cl)-OH·DCHA
5-04231 1g Ask for price

Ac-DL-Trp(5-Cl)-OH·DCHA
5-04232 5g Ask for price

Fmoc-2-amino-5-Methoxybenzoic acid
5-04549 1g Ask for price

Fmoc-2-amino-5-Methoxybenzoic acid
5-04550 5g Ask for price

Fmoc-3-Ala(5-Thiazoyl)-OH
5-05361 1g Ask for price

Fmoc-3-Ala(5-Thiazoyl)-OH
5-05362 5g Ask for price

7078D 5 PIPET 5ML STERILE STERILE
7078D-5 25/pk
EUR 217
Description: Disposable Pipets; Disposable Pipets, Serological, Misc

Beta-Sheet Breaker Peptide iA?5
A1005-5 5 mg
EUR 102
Description: Beta-Sheet Breaker Peptide iA?5 (C33H43N5O8), with the sequence H-Leu-Pro-Phe-Phe-Asp-OH, has been shown to inhibit amyloidogenesis in rat brain models.

2'-Fluoro-2'-deoxyadenosine-5'-Triphosphate
B7959-.5 5x100 µl (100 mM)
EUR 2059

2'-Fluoro-2'-deoxycytidine-5'-Triphosphate
B7961-.5 5x100 µl (100 mM)
EUR 2059

2'-Fluoro-2'-deoxyguanosine-5'-Triphosphate
B7962-.5 5x100 µl (100 mM)
EUR 2059

2'-Fluoro-2'-deoxyuridine-5'-Triphosphate
B7963-.5 5x100 µl (100 mM)
EUR 2059

3-bromo-5-phenyl Salicylic Acid
C4516-5 5 mg
EUR 370
Description: Ki: 140 nM for AKR1C1; 1.97 ?M for AKR1C2; 21 ?M for AKR1C3 3-bromo-5-phenyl Salicylic acid is an AKR1C1 inhibitor.

5-bromo-3-phenyl Salicylic Acid
C4610-5 5 mg
EUR 319

5-(N,N-dimethyl)-Amiloride (hydrochloride)
C3505-5 5 mg
EUR 180
Description: 5-(N, N-dimethyl)-Amiloride (hydrochloride), a derivative of amiloride, is an inhibitor of NHE1, NHE2, and NHE3. The Na+/H+ exchanger (NHE) is a protein that has been involved in intracellular pH homeostasis of many mammalian cell types.

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 x 5 preps)
CBA-155-5 25 preps
EUR 3245
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

5-Hydroxytryptamine (5-HT) ELISA Kit
DLR-5-HT-Ge-48T 48T
EUR 469
Description: A competitive inhibition quantitative ELISA assay kit for detection of 5-Hydroxytryptamine (5-HT) in samples from serum, plasma or other biological fluids.

5-Hydroxytryptamine (5-HT) ELISA Kit
DLR-5-HT-Ge-96T 96T
EUR 608
Description: A competitive inhibition quantitative ELISA assay kit for detection of 5-Hydroxytryptamine (5-HT) in samples from serum, plasma or other biological fluids.

S-(5'-Adenosyl)-L-methionine chloride (hydrochloride)
B2826-5
EUR 120

[D-Ala2]- beta-Casomorphin (1-5), bovine
5-00075 4 x 5mg Ask for price

[D-Pro2]-beta-Casomorphin (1-5) , bovine
5-00133 4 x 5mg Ask for price

beta-Endorphin (1-5) + (16-31), human
5-00488 4 x 1mg Ask for price

The National Task Force for Covid-19 of the Indian Council of MedicalResearch (ICMR) in a bulletin dated March 21, 2020 really useful the use of hydroxychloroquine for prophylaxis in asymptomatic well being care staff caring for suspected or confirmed sufferers and family contacts of confirmed sufferers. This is trigger for concern with regard to bioethics and good medical follow.

The proof for the efficacy of chloroquine and hydroxychloroquine is at the moment derived from open label trials and cell tradition research with no conclusive proof accessible from randomised medical trials.

Hydroxychloroquine additionally carries contraindications in the case of situations corresponding to maculopathy, retinopathy and QTc prolongation and must be used with warning in susceptible populations corresponding to kids, being pregnant, lactation and the aged. Despite this, there was a rush to obtain and self-medicate with hydroxychloroquine, which has been addressed by the National Task Force.

The WHO and the FDA haven’t discovered sufficient proof to advocate any particular medicine for the remedy of Covid-19. While additional proof is awaited, together with from trials registered with the FDA and the ICMR, it’s endorsed that the administration of hydroxychloroquine for chemo-prophylaxis be thought of on a case by case foundation with monitoring by a registered medical practitioner together with electrocardiography (ECG).

The potential for retinal and cardiac toxicity should even be borne in thoughts. It is additional really useful {that a} public advisory concerning the want for warning in chemo-prophylaxis be made accessible in the public area. Keywords: Coronavirus, Covid-19, SARS-CoV-2, hydroxychloroquine, chloroquine, chemoprophylaxis, bioethics, evidence- based mostly medication.